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The Research Behind
the Protocol

Every performance claim on the Beetroot Pro® site is anchored to a specific peer-reviewed study indexed on PubMed. The 16 citations below cover the dietary nitrate / nitric oxide pathway, beta-alanine carnosine buffering, creatine ATP resynthesis, cordyceps mitochondrial efficiency, sweat-rate research, and the IOC 2018 consensus on supplements with evidence for endurance performance.

No marketing dressed as science. Browse the full library below.

16 clinical references
16 PubMed-indexed
Nitrate & Nitric Oxide Physiology

Dietary nitrate supplementation reduces the oxygen cost of exercise, improves time-trial performance, and supports cardiovascular function through the nitrate-nitrite-NO pathway.

Bailey SJ, et al.

Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans

Journal of Applied Physiology · 2009

PMID 19661447 DOInitrate nitric oxide

Lansley KE, et al.

Acute dietary nitrate supplementation improves cycling time trial performance

Medicine & Science in Sports & Exercise · 2011

PMID 21471821nitrate nitric oxide

Lansley KE, et al.

Dietary nitrate supplementation reduces the O2 cost of walking and running

Journal of Applied Physiology · 2011

PMID 21071588nitrate nitric oxide

Jones AM.

Dietary nitrate supplementation and exercise performance

Sports Medicine · 2014

PMID 24791915 DOInitrate nitric oxide

Larsen FJ, et al.

Effects of dietary nitrate on blood pressure in healthy volunteers

New England Journal of Medicine · 2006

PMID 17192551nitrate nitric oxide

Govoni M, et al.

The increase in plasma nitrite after a dietary nitrate load is markedly attenuated by an antibacterial mouthwash

Nitric Oxide · 2008

PMID 18793740nitrate nitric oxide

Wylie LJ, et al.

Beetroot juice and exercise: pharmacodynamic and dose-response relationships

Journal of Applied Physiology · 2013

PMID 23640589dosing pharmacokinetics
Masters Athletes & Longevity

eNOS activity declines with age, reducing endogenous NO production. Dietary nitrate provides an eNOS-independent pathway that is especially relevant for athletes over 35.

Taddei S, et al.

Age-related reduction of NO availability and oxidative stress in humans

Hypertension · 2001

PMID 11509489masters longevity

Tanaka H, Seals DR.

Endurance exercise performance in Masters athletes: age-associated changes and underlying physiological mechanisms

Journal of Physiology · 2008

PMID 17717011masters longevity
Beta-Alanine & Lactic Acid Buffering

Beta-alanine supplementation elevates muscle carnosine, buffering hydrogen ions during high-intensity exercise. Meta-analyses confirm performance improvements in efforts lasting 1-4 minutes.

Harris RC, et al.

The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis

Amino Acids · 2006

PMID 16554972beta alanine

Hoffman JR, et al.

Short-duration beta-alanine supplementation increases training volume and reduces subjective feelings of fatigue in college football players

Nutrition Research · 2008

PMID 19083385beta alanine

Hoffman JR, et al.

Effect of betaine supplementation on power performance and fatigue

Journal of the International Society of Sports Nutrition · 2009

PMID 19250531beta alanine

Hobson RM, et al.

Effects of beta-alanine supplementation on exercise performance: a meta-analysis

Amino Acids · 2012

PMID 22270875beta alanine

Saunders B, et al.

Beta-alanine supplementation to improve exercise capacity and performance: a systematic review and meta-analysis

British Journal of Sports Medicine · 2017

PMID 27797728beta alanine
Supplement Safety & Compliance

Commercial beetroot products vary 100-fold in actual nitrate content. The IOC consensus framework evaluates supplement efficacy, safety, and prohibited-substance risk for elite athletes.

Gallardo EJ, Coggan AR.

What's in Your Beet Juice? Nitrate and Nitrite Content of Beet Juice Products Marketed to Athletes

International Journal of Sport Nutrition and Exercise Metabolism · 2019

PMID 30299195supplement safety

IOC Consensus Panel (Maughan RJ, et al.)

IOC consensus statement: dietary supplements and the high-performance athlete

International Journal of Sport Nutrition and Exercise Metabolism · 2018

PMID 29589768 DOIioc consensus

Put the Research Into Practice

Disclosed doses you can verify on the label. Every batch ISO 17025 tested.

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