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Evidence-Based

The Research Behind
the Protocol

Every claim on Beetroot Pro references a specific clinical study indexed on PubMed. No marketing dressed as science. Browse the full library below.

17 clinical references
5 PubMed-indexed
Nitrate & Nitric Oxide Physiology

Dietary nitrate supplementation reduces the oxygen cost of exercise, improves time-trial performance, and supports cardiovascular function through the nitrate-nitrite-NO pathway.

Bailey SJ, et al.

Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans

Journal of Applied Physiology · 2009

PMID 19407244 DOInitrate nitric oxide

Lansley KE, et al.

Acute dietary nitrate supplementation improves cycling time trial performance

Journal of Applied Physiology · 2011

PMID 20947715nitrate nitric oxide

Lansley KE, et al.

Dietary nitrate supplementation reduces the O2 cost of walking and running

Journal of Applied Physiology · 2011

nitrate nitric oxide

Jones AM.

Dietary nitrate supplementation and exercise performance

Sports Medicine · 2014

PMID 24338227 DOInitrate nitric oxide

Larsen FJ, et al.

Effects of dietary nitrate on blood pressure in healthy volunteers

New England Journal of Medicine · 2007

PMID 17450101nitrate nitric oxide

Govoni M, et al.

The increase in plasma nitrite after a dietary nitrate load is markedly attenuated by an antibacterial mouthwash

Nitric Oxide · 2008

nitrate nitric oxide

Wylie LJ, et al.

Beetroot juice and exercise: pharmacodynamic and dose-response relationships

Journal of Applied Physiology · 2013

dosing pharmacokinetics

Jonvik KL, et al.

Plasma nitrite pharmacokinetics for extract versus juice delivery formats

Nitric Oxide · 2020

dosing pharmacokinetics
Masters Athletes & Longevity

eNOS activity declines with age, reducing endogenous NO production. Dietary nitrate provides an eNOS-independent pathway that is especially relevant for athletes over 35.

Taddei S, et al.

Age-related reduction of NO availability and oxidative stress in humans

Hypertension · 2001

masters longevity

Tanaka H, Seals DR.

Endurance exercise performance in Masters athletes: age-associated changes and underlying physiological mechanisms

Journal of Physiology · 2008

masters longevity
Beta-Alanine & Lactic Acid Buffering

Beta-alanine supplementation elevates muscle carnosine, buffering hydrogen ions during high-intensity exercise. Meta-analyses confirm performance improvements in efforts lasting 1-4 minutes.

Harris RC, et al.

The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis

Amino Acids · 2006

beta alanine

Hoffman JR, et al.

Short-duration beta-alanine supplementation increases training volume and reduces subjective feelings of fatigue

Journal of the International Society of Sports Nutrition · 2008

beta alanine

Hoffman JR, et al.

Effect of betaine supplementation on power performance and fatigue

Journal of the International Society of Sports Nutrition · 2009

beta alanine

Hobson RM, et al.

Meta-analysis of beta-alanine supplementation and exercise performance

Amino Acids · 2012

beta alanine

Saunders B, et al.

Beta-alanine supplementation to improve exercise capacity and performance: a systematic review and meta-analysis

British Journal of Sports Medicine · 2017

beta alanine
Supplement Safety & Compliance

Commercial beetroot products vary 100-fold in actual nitrate content. The IOC consensus framework evaluates supplement efficacy, safety, and prohibited-substance risk for elite athletes.

PMC Open Access (2021)

Survey of dietary nitrate content in commercial beetroot products

Peer-reviewed clinical survey · 2021

supplement safety

IOC Consensus Panel (Maughan RJ, et al.)

IOC consensus statement: dietary supplements and the high-performance athlete

International Journal of Sport Nutrition and Exercise Metabolism · 2018

PMID 29745784 DOIioc consensus

Put the Research Into Practice

Clinically dosed supplements you can trust. Every batch ISO 17025 tested.

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